Evaluation Of Calcium / Magnesium Ratio İn Patients With Type 2 Diabetes Mellitus
Özet
magnesium
(Ca/Mg) ratio in patients diagnosed with type 2 diabetes
mellitus (T2DM).
Methods: This study is a retrospective cross-sectional study.
Mg levels were determined by measuring the total serum
Mg levels. Magnesium was measured by colorimetric method
and HbA1c was measured by turbidimetric inhibition immunoassay
method. Subject were divided into two groups (<7%
and ≥7%) based on HbA1c levels. Also, subjects were divided
into four groups (quartiles) based on serumMg concentrations.
Results: A total of 891 (636F, 255M) patients diagnosed with
T2DM were included in the study. The Mg increase in the
group with good glycemic control was also remarkable. One
of our most important findings is that as the Mg concentration
increases, the fasting glucose, HbA1c, and Ca/Mg rate
decreased with increasing Mg concentration. In the ROC
analysis performed between the poor and good glycemic
control groups, we found the AUC was 0.672, 0.650, 0.611, and
0.578 for Ca/Mg ratio, Mg, K, and Ca, respectively.
Conclusions: While the Ca/Mg ratio and Ca levels were
significantly higher, Mg levels were significantly lower
among poor glycemic control than good glycemic control
T2DM. The Ca/mg ratio and Mg are important parameters for
T2DM patients, but more comprehensive studies are needed
before they can monitor glycemic control.
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