Osteoporosis risk of the subjects with isolated lactase enzyme deficiency

Abstract

I have read Treister-Goltzman Y’s article with a great interest since I have been working on the answer whether physicians have to treat the patients with isolated lactase enzyme deficiency [1]. By isolated lactase enzyme deficiency, I would rather refer to the patients with lactase deficiency determined by objective diagnostic tools, e.g., genetic analyses, direct enzyme activity measurement through intestinal biopsy or H2 breath test, whereas presenting no lactose intolerance related symptoms [2, 3]. Most of these patients are diagnosed during the lactose intolerance evaluation due to the family history.